Protecting Groups: Strategies and Applications in Carbohydrate Chemistry
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保護基:炭水化物化学における戦略と応用 Publisher: VCH ISBN: 9783527340101 Cover: HARDCOVER Date: 2019年01月 こちらの商品は学校・法人様向け(機関契約)のオンラインブック版がございます。 オンラインブックの価格、納期につきましては弊社営業員または当ECサイトよりお問い合わせください。 DESCRIPTION A unique overview of the most important protecting group strategies in carbohydrate chemistry Protecting Groups: Strategies and Applications in Carbohydrate Chemistry provides a detailed account of key strategies and methodologies for the protection of carbohydrates. Divided into two parts, the first focuses on groups that are used best to protect a specific position on a carbohydrate. In the second part, specific carbohydrate residues or compounds are discussed in the context of a specific protecting group strategy used to reach the desired regioisomer. This important book: -Features chapters on protecting groups at the primary and secondary positions of carbohydrates -Describes protecting group strategies towards sialic acid derivatives, glycofuranoses, sulfated glycosaminoglycans, and cyclodextrins -Provides information on automated glycan assembly -Includes a chapter on the industrial scale synthesis of heparin analogs Written by a team of leaders in the field, Protecting Groups: Strategies and Applications in Carbohydrate Chemistry is an indispensable guide for academics and industrial researchers interested in carbohydrate and natural product synthesis, pharmaceutical chemistry, and biochemistry. TABLE OF CONTENTS 1 Protecting Group Strategies in Carbohydrate Chemistry 1 2 Protecting Groups at the Primary Position of Carbohydrates 29 3 Protecting Groups at the Secondary Positions of Carbohydrates 69 4 Regioselective Protection at the Secondary Positions of Carbohydrates with Acyclic Protecting Groups 109 5 Protecting Groups at the Anomeric Position of Carbohydrates 145 6 N‐protecting Groups for 2‐Amino‐2‐deoxy‐glycosides 169 7 One‐pot Multistep Regioselective Protection of Carbohydrates Catalyzed by Acids 201 8 Acyl Migrations in Carbohydrate Chemistry 227 9 De Novo Asymmetric Synthesis of Oligosaccharides Using Atom‐less Protecting Groups 243 10 Protecting Group Strategies for Sialic Acid Derivatives 283 11 Strategies Toward Protection of 1,2‐ and 1,3‐Diols in Carbohydrate Chemistry 307 12 Protecting Group Strategies Toward Glycofuranoses 337 13 Cyclodextrin Chemistry via Selective Protecting Group Manipulations 371 14 Protecting Group Strategies Toward Sulfated Glycosaminoglycans 395 15 Applications of Fluorous and Ionic Liquid Tags in Oligosaccharide Synthesis 423 16 Orthogonally Protected Building Blocks for Automated Glycan Assembly 451 17 Kilogram‐scale Production of Synthetic Heparin Analogs: Some Chemical Considerations 473
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