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Greene's Protective Groups in Organic Synthesis, 2 Volume Set, 6 ed
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グリーン有機合成における保護基 第6版 全2巻 Author: Wuts, Peter G. M. (Kalamazoo, Michigan, USA) Publisher: WILEY ISBN: 9781394233168 Cover: HARDCOVER Date: 2025年04月 DESCRIPTION グリーンの有機合成における保護基 11年ぶりの改訂版！ 有機合成の複雑さを乗り越えるための決定版リファレンスです。 保護基の分類や応用に関する最新のガイダンスを提供しています。 保護が必要な官能基ごとに整理された詳細な解説により、有機合成に携わるすべての化学者にとって必携の一冊となっています。革新的な有機化合物の創出に不可欠なリソースであり、最新の改訂版では、炭水化物化学における保護基の影響が反応性や選択性にどのように関与するかを扱う新章を追加。 Dintegral, reliable, and comprehensive guidance for chemists performing the complex syntheses required for the formation and cleavage of protective groups Organic synthesis is the preparation and creation of organic compounds for use in natural products, pharmaceuticals, and other molecules. The synthesis of molecules having multiple functional groups often requires the use of “protective groups” to achieve site selectivity in a chemical reaction within a molecule bearing multiple sites of reactivity. Protective groups are installed temporarily to prevent unwanted reactions at a particular site, while transforming a different functional group. Once they have served their function, they are removed to expose the original group. Without a thorough understanding of the methods required to install and remove them, the design of a synthesis of a molecule having multiple functional groups in most cases is effectively impossible. Greene's Protective Groups in Organic Synthesis, 6th Edition is the definitive compilation of protective groups, their classification, and their application in a wide array of situations. With a long tradition of comprehensive coverage, organized on the basis of the functional group in need of protection and subsequent deprotection, it is an essential reference and resource for all chemists involved in organic syntheses. Now fully updated to reflect the current state of the art, it remains an indispensable resource for generating life-changing organic products. This edition contains a new chapter on how protective groups effect reactivity and selectivity in carbohydrate chemistry. Readers of the sixth edition of Greene's Protective Groups in Organic Synthesis will also find: * Methodology for planning selectivity in organic syntheses * Detailed discussion of all major functional groups including ethers, amides, and phenols * A discussion of the impact of protective groups on reactivity in carbohydrates Greene's Protective Groups in Organic Synthesis is ideal for synthetic organic chemists or medicinal chemists in academia, industry-pharmaceuticals, food, agrochemicals, and biotech-or government agencies. TABLE OF CONTENTS Volume 1 1. The Role of Protective Groups in Organic Synthesis 2. Protection for the Hydroxyl Group Including 12- and 13- Diols 3. Protection for Phenols and Catechols 4. Protection for the Carbonyl Group 5. Protection for the Carboxyl Group 6. Protection for the Thiol Group Volume 2 7. Protection for the Amino Group 8. Protection for the Alkyne ─CH 9. Protection for the Phosphate Group 10. Protecting Group Effects in Carbohydrate Chemistry 11. Reactivities Reagents and Reactivity Charts
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